CLINICAL TRIAL SUMMARY

MDACC Study No:2013-0324 (clinicaltrials.gov NCT No: NCT01928537)
Title:Phase IIIB, Open-label, Multi-Center Study of the Efficacy and Safety of Rigosertib Administered as 72-hour Continuous Intravenous Infusions in Patients with Myelodysplastic Syndrome with Excess Blasts Progressing On or After Azacitidine or Decitabine
Principal Investigator:Guillermo Garcia-Manero
Treatment Agent:RIGOSERTIB SODIUM (ON 01910.Na)
Study Status:Open
Study Description:Patients with MDS often need blood cell transfusions to prevent diseases like
anemia (low red blood cell counts), bleeding, and/or serious infections.
However, these transfusions can lead to collections of abnormal cells, called
blasts, which can put you at a higher risk for developing leukemia.

The goal of this clinical research study is to learn if rigosertib can help to
control MDS in patients with an unusual number of blasts. The safety of this
drug will also be studied.

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Disease Group:Leukemia
Phase of Study:Phase III
Treatment Agents:RIGOSERTIB SODIUM (ON 01910.Na)
Treatment Location:Both at MDACC & and Other Sites
Estimated Length of Stay in Houston:
Supported By:Onconova Therapeutics Inc.
Return Visit:
Home Care:


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Physician Name:Guillermo Garcia-Manero
Dept:Leukemia
For Clinical Trial Enrollment:713-745-3428
For General Questions about Clinical Trials:1-877-MDA-6789


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