Basic and Laboratory Research

Cancer Biology

Isaiah J. Fidler. Selection of successive tumor lines for metastasis

Isaiah J. Fidler, Margaret L. Kripke. Metastasis results from preexisting variant cells within a malignant tumor

James E. Talmadge, Sandra R. Wolman, Isaiah J. Fidler. Evidence for the clonal origin of spontaneous metastasis

Ian R. Hart, Isaiah J. Fidler. Role of organ selectivity in the determination of metastatic patterns of the B16 melanoma

Isaiah J. Fidler, Ian R. Hart. Biological diversity in metastatic neoplasms: Origins and implications

Isaiah J. Fidler. The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited

Jennifer D. Cook, Barbara J. Davis, Sheng-Li Cai, J. Carl Barrett, Claudio J. Conti, Cheryl Lyn Walker. Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance

Cheryl Lyn Walker, Elizabeth A. Stewart. Uterine fibroids: The elephant in the room

Shigetoshi Sano, Keith Syson Chan, Steve Carbajal, John Clifford, Mary Peavey, Kaoru Kiguchi, Satoshi Itami, Brian J. Nickoloff, John DiGiovanni. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

Yutaka Takahashi, Yasuhiko Kitadai, Corazon D. Bucana, Karen R. Cleary, Lee M. Ellis. Expression of vascular endothelial growth factor and its receptor (KDR) correlates with vascularity, metastasis and proliferation of human colon cancer

Genetics

Guliang Wang, Laura A. Christensen, Karen M. Vasquez. Z-DNA-forming sequences generate large-scale deletions in mammalian cells

Guliang Wang, Karen M. Vasquez. Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells

Gene A. Lang, Tomoo Iwakuma, Young-Ah Suh, Geng Liu, V. Ashutosh Rao, John M. Parant, Yasmine A. Valentin-Vega, Tamara Terzian, Lisa C. Caldwell, Louise C. Strong, Adel K. El-Naggar, Guillermina Lozano. Gain-of-function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome

Amr S. Soliman, Melissa L. Bondy, Samy A. El-Badawy, Nadia Mokhtar, Sanaa Eissa, Shariff Bayoumy, Ibrahim A. Seifeldin, P. Scott Houlihan, Jeffrey R. Lukish, Toshiaki Watanabe, Annie O. Chan, Dakai Zhu, Christopher I. Amos, Bernard Levin, Stanley R. Hamilton. Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients

Annie O. Chan, Amr S. Soliman, Qing Zhang, Asif Rashid, Ahmed Bedeir, P. Scott Houlihan, Nadia Mokhtar, Nidal Al-Masri, Ugur Ozbek, Rami Yaghan, Ayten Kandilci, Sherif Omar, Yersu Kapran, Ferhunde Dizdaroglu, Melissa L. Bondy, Christopher I. Amos, Jean-Pierre Issa, Bernard Levin, Stanley R. Hamilton. Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries

Lanlan Shen, Yutaka Kondo, Gary L. Rosner, Lianchun Xiao, Natalie Supunpong Hernandez, Jill Vilaythong, P. Scott Houlihan, Robert S. Krouse, Anil R. Prasad, Janine G. Einspahr, Julie Buckmeier, David S. Alberts, Stanley R. Hamilton, Jean-Pierre Issa. MGMT promoter methylation and field defect in sporadic colorectal cancer

Jean-Pierre Issa. Epigenetic variation and human disease

Bogdan Czerniak, Li Li, Vijaya Chaturvedi, J. Y. Ro, Dennis A. Johnston, Sherie Hodges, William F. Benedict. Genetic modeling of human urinary bladder carcinogenesis

Tomasz Tuziak, Joon Jeong, Tadeusz Majewski, Mi-Sook Kim, Jordan Steinberg, Zhi Wang, Dong-Sup Yoon, Tang C. Kuang, Keith Baggerly, Dennis Johnston, Bogdan Czerniak. High-resolution whole-organ mapping with SNPs and its significance to early events in carcinogenesis

Peter A. Steck, Mark A. Pershouse, Sammar A. Jasser, W. K. Alfred Yung, Hual Lin, Azra H. Ligon, Lauren A. Langford, Michelle L. Baumgard, Thomas Hattier, Thaylon Davis, Cheryl Frye, Rong Hu, Bradley Swedlund, David H.R. Teng, Sean V. Tavtigian. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Honnavara N. Ananthaswamy, Stephen E. Ullrich, Romano E. Mascotto, Anny Fourtanier, Susan M. Loughlin, Polina Khaskina, Corazon D. Bucana, Margaret L. Kripke. Inhibition of solar simulator-induced p53 mutations and protection against skin cancer development in mice by sunscreens

Honnavara N. Ananthaswamy, Susan M. Loughlin, Stephen E. Ullrich, Margaret L. Kripke. Inhibition of UV-induced p53 mutations by sunscreens: Implications for skin cancer prevention

Honnavara N. Ananthaswamy, Susan M. Loughlin, Patricia Cox, Randall L. Evans, Stephen E. Ullrich, Margaret L. Kripke. Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens

Feng Lin, Giuseppe Monaco, Tong Sun, Jiaxin Liu, Hui Lin, Clifton Stephens, John Belmont, Ralph B. Arlinghaus. BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model

Natalyn Hawk, Tong Sun, Shanhai Xie, Yan Wang, Yun Wu, Jiaxin Liu, Ralph B. Arlinghaus. Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354

Loretta Raycroft, Hung-Yi Wu, Guillermina Lozano. Transcriptional activation by wild-type but not transforming mutants of the p53 antioncogene

Loretta Raycroft, Juliann R. Schmidt, Karen Yoas, Mingming Hao, Guillermina Lozano. Analysis of p53 mutants for transcriptional activity

Roberta Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano. Rescue of early embryonic lethality in mdm-2-deficient mice by deletion of p53

John Parant, Arturo Chavez-Reyes, Natalie A. Little, Wen Yan, Valerie Reinke, Aart G. Jochemsen, Guillermina Lozano. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a non-overlapping pathway with MDM2 to regulate p53

Kirsten K. Youngren, Douglas Coveney, Xiaoning Peng, Chitralekha Bhattacharya, Laura S. Schmidt, Michael L. Nickerson, Bruce T. Lamb, Jian Min Deng, Richard R. Behringer, Blanche Capel, Edward M. Rubin, Joseph H. Nadeau, Angabin Matin. The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours

Ling Wu, Asha S. Multani, Hua He, Wilfredo Cosme-Blanco, Yu Deng, Jian Min Deng, Olga Bachilo, Sen Pathak, Hidetoshi Tahara, Susan M. Bailey, Yibin Deng, Richard R. Behringer, Sandy Chang. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

Hua He, Asha S. Multani, Wilfredo Cosme-Blanco, Hidetoshi Tahara, Jin Ma, Sen Pathak, Yibin Deng, Sandy Chang. Pot1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination

Molecular Biology

Shlaw-Yih Lin, Keishi Makino, Weiya Xia, Angabin Matin, Yong Wen, Ka Yin Kwong, Lilly Bourguignon, Mien-Chie Hung. Nuclear localization of EGF receptor and its potential new role as a transcription factor

Shao-Chun Wang, Ysuske Nakajima, Yung-Luen Yu, Weiya Xia, Chun-Te Chen, Cheng-Chieh Yang, Eric W. McIntush, Long-Yuan Li, David H. Hawke, Ryuji Kobayashi, Mien-Chie Hung. Tyrosine phosphorylation controls protein stability of PCNA

Hui-Wen Lo, Sheng-Chieh Hsu, Mohamed Ali-Seyed, Mehmet Gunduz, Weiya Xia, Yongkun Wei, Geoffrey Bartholomeusz, Jin-Yuan Shih, Mien-Chie Hung. Nuclear interaction of EGFR and STAT3 in the activation of iNOS/NO pathway

Rakesh Kumar, Rui-An Wang, Abhijit Mazumdar, Amjad H. Talukder, Mahintosh Mandal, Zhibo Yang, Rozita Bagheri-Yarmand, Aysegul Sahin, Gabriel N. Hortobagyi, Liana Adam, Christopher J. Barnes, Ratna K. Vadlamudi. A naturally occurring MTA1 variant sequesters estrogen receptor-alpha in the cytoplasm

Kazuhisa Nakashima, Xin Zhou, Gary Kunkel, Zhaoping Zhang, Jian Min Deng, Richard R. Behringer, Benoit de Crombrugghe. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

Takako Koga, Yuichi Matsui, Masataka Asagiri, Tatsuhiko Kodama, Benoit de Crombrugghe, Kazuhisa Nakashima, Hiroshi Takayanagi. NFAT and Osterix cooperatively regulate bone formation

Yao-Fu Chang, J. Saadi Imam, Miles F. Wilkinson. The nonsense-mediated decay RNA surveillance pathway

Wai-Kin Chan, Lulu Huang, Jayanthi P. Gudikote, Yao-Fu Chang, J. Saadi Imam, James A. MacLean II, Miles F. Wilkinson. An alternative branch of the nonsense-mediated decay pathway

Jayanthi R. Gudikote, J. Saadi Imam, Ramon F. Garcia, Miles F. Wilkinson. RNA splicing promotes translation and RNA surveillance

Developmental Biology

Yumi Watanabe, Sei Kameoka, Vidya Gopalakrishnan, Kenneth D. Aldape, Zhizhong Z. Pan, Frederick F. Lang, Sadhan Majumder. Conversion of myoblasts to physiologically active neuronal phenotype

Matus Studeny, Frank C. Marini, Jennifer L. Dembinski, Claudia Zompetta, Maria Cabreira-Hansen, Benjamin Nebiyou Bekele, Richard E. Champlin, Michael Andreeff. Mesenchymal stem cells: Potential precursors for tumor stroma and targeted delivery vehicles of anti-cancer agents

Kensuke Kojima, Marina Konopleva, Ismael J. Samudio, Masato Shikami, Maria Cabreira-Hansen, Teresa McQueen, Vivian Ruvolo, Twee Tsao, Zhihong Zeng, Lyubomir T. Vassilev, Michael Andreeff. MDM2 antagonists induce p53-dependent apoptosis in AML: Implications for leukemia therapy

Immunology

Stephen E. Ullrich. Mechanisms underlying UV-induced immune suppression [review]

Norihiko Watanabe, Yi-Hong Wang, Heung Kyu Lee, Tomoki Ito, Yui-Hsi Wang, Wei Cao, Yong-Jun Liu. Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

Wei Cao, David B. Rosen, Tomoki Ito, Laura Bover, Musheng Bao, Gokuran Watanabe, Zhengbin Yao, Li Zhang, Lewis L. Lanier, Yong-Jun Liu. Plasmacytoid dendritic cell-specific receptor ILT7/Fc RI inhibits toll-like receptor-induced interferon production

Wei Cao, Li Zhang, David B. Rosen, Laura Bover, Gokuran Watanabe, Musheng Bao, Lewis L. Lanier, Yong-Jun Liu. BDCA2/FceRlg complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells

Claudia M. Kowolik, Max S. Topp, Sergio Gonzalez, Timothy Pfeiffer, Simon Olivares, Nancy Gonzalez, David D. Smith, Stephen J. Forman, Michael C. Jensen, Laurence J. N. Cooper. CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells

Preclinical Development of Novel Therapies

Marco A. Arap, Johanna Lahdenranta, Paul J. Mintz, Amin Hajitou, Álvaro S. Sarkis, Wadih Arap, Renata Pasqualini. Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

Mikhail G. Kolonin, Pradip K. Saha, Lawrence Chan, Renata Pasqualini, Wadih Arap. Reversal of obesity by targeted ablation of adipose tissue

Pramod N. Nehete, Eric M. Vela, M. M. Hossain, Asis K. Sarkar, Nouara Yahi, Jacques Fantini, K. Jagannadha Sastry. A post-CD4-binding step involving interaction of the V3 region of viral gp120 with host cell surface glycosphingolipids is common to entry and infection by diverse HIV-1 strains

Pramod N. Nehete, Ralph B. Arlinghaus, K. Jagannadha Sastry. Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120

Yoichi Nagata, Keng-Hsueh Lan, Xiaoyan Zhou, Ming Tan, Francisco J. Esteva, Aysegul A. Sahin, Kristine S. Klos, Ping Li, Brett P. Monia, Nina T. Nguyen, Gabriel N. Hortobagyi, Mien-Chie Hung, Dihua Yu. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Detection, Predicting Outcomes, and Risk Assessment

Massimo Cristofanilli, G. Thomas Budd, Matthew J. Ellis, Alison Stopeck, Jeri Matera, M. Craig Miller, James M. Reuben, Gerald V. Doyle, W. Jeffrey Allard, Leon W. M. M. Terstappen, Daniel F. Hayes. Circulating tumor cells predict progression free survival and overall survival in metastatic breast cancer

Khandan Keyomarsi, Susan L. Tucker, Thomas A. Buchholz, Matthew Callister, Ye Ding, Gabriel N. Hortobagyi, Isabelle Bedrosian, Christopher Knickerbocker, Wendy Toyofuku, Michael Lowe, Thaddeus W. Herliczek, Sarah S. Bacus. Cyclin E and survival in patients with breast cancer

Li Mao, Jin Soo Lee, Jonathan M. Kurie, You Hong Fan, Scott M. Lippman, J. Jack Lee, Jae Y. Ro, Anita Broxson, Ren Yu, Rodolfo C. Morice, Bonnie L. Kemp, Fadlo R. Khuri, Garrett L. Walsh, Walter N. Hittelman, Waun-Ki Hong. Clonal genetic alterations in the lungs of current and former smokers

Lei L. Chen, Jonathan C. Trent, Elsie F. Wu, Gregory N. Fuller, Latha Ramdas, Wei Zhang, Austin K. Raymond, Victor G. Prieto, Caroline O. Oyedeji, Kelly K. Hunt, Raphael E. Pollock, Barry W. Feig, Kimberly J. Hayes, Haesun Choi, Homer A. Macapinlac, Walter Hittelman, Marco A. Velasco, Shreyaskumar Patel, Michael A. Burgess, Robert S. Benjamin, Marsha L. Frazier. A missense mutation in kit kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors

Kenneth R. Hess, Keith Anderson, W. Fraser Symmans, Vicente Valero, Nuhad Ibrahim, Jaime A. Mejia, Daniel Booser, Richard L. Theriault, Aman U. Buzdar, Peter J. Dempsey, Roman Rouzier, Nour Sneige, Jeffrey S. Ross, Tatiana Vidaurre, Henry L. Gómez, Gabriel N. Hortobagyi, Lajos Pusztai. Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer

Roman Rouzier, Charles M. Perou, W. Fraser Symmans, Nuhad Ibrahim, Massimo Cristofanilli, Keith Anderson, Kenneth R. Hess, James Stec, Mark Ayers, Peter Wagner, Paolo Morandi, Chang Fan, Islam Rabiul, Jeffrey S. Ross, Gabriel N. Hortobagyi, Lajos Pusztai. Breast cancer molecular subtypes respond differently to preoperative chemotherapy

Roman Rouzier, Radhika Rajan, Peter Wagner, Kenneth R. Hess, David L. Gold , James Stec, Mark Ayers, Jeffrey S. Ross, Peter Zhang, Thomas A. Buchholz, Henry Kuerer, Marjorie Green, Banu Arun, Gabriel N. Hortobagyi, W. Fraser Symmans, Lajos Pusztai. Microtubule-associated protein tau: A marker of paclitaxel sensitivity in breast cancer

Imad Shureiqi, Wei Jiang, Xiangsheng Zuo, Yuanqing Wu, Julie B. Stimmel, Lisa M. Leesnitzer, Jeffrey S. Morris, Hui-Zhen Fan, Susan M. Fischer, Scott M. Lippman. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells

Xifeng Wu, Jian Gu, H. Barton Grossman, Christopher I. Amos, Carol Etzel, Maosheng Huang, Qing Zhang, Randal E. Millikan, Seth Lerner, Colin P. Dinney, Margaret R. Spitz. Bladder cancer predisposition: A multigenic approach to DNA-repair and cell-cycle–control genes

Sara S. Strom, Xuemei Wang, Curtis A. Pettaway, Christopher J. Logothetis, Yuko Yamamura, Kim-Anh Do, Richard J. Babaian, Patricia Troncoso. Obesity, weight gain and risk of biochemical failure among prostate cancer patients following prostatectomy

Jun-Qing Guo, Jidong Lian, Amanda Glassman, Moshe Talpaz, Hagop M. Kantarjian, Albert B. Deisseroth, Ralph B. Arlinghaus. Comparison of Bcr-Abl protein expression and Philadelphia chromosome analyses in chronic myelogenous leukemia patients

Jun-Qing Guo, Huixian Lin, Hagop M. Kantarjian, Moshe Talpaz, Richard Champlin, Michael Andreeff, Amanda Glassman, Ralph B. Arlinghaus. Comparison of competitive-nested PCR and real-time PCR in detecting of Bcr-Abl fusion transcripts in chronic myeloid leukemia patients

Chang JP, Russell WO, Moore EB, Sinclair WK. A new cryostat for frozen section technic. Am J Clin Path. 1961; 35(1):14-19.

Cancer Prevention

Carlos H. Barcenas, Anna V. Wilkinson, Sara S. Strom, Yumei Cao, Katherine C Saunders, Somdat Mahabir, María A. Hernández-Valero, Michele R. Forman, Margaret R. Spitz, Melissa L. Bondy. Birthplace, years of residence in the United States, and obesity among Mexican-American adults

Anna V. Wilkinson, Margaret R. Spitz, Sara S. Strom, Alexander V. Prokhorov, Carlos H. Barcenas, Yumei Cao, Katherine C. Saunders, Melissa L. Bondy. Effects of nativity, age at migration, and acculturation on smoking among adult Houston residents of Mexican descent

Waun-Ki Hong, Jean Endicott, Loretta M. Itri, Wilhelm G. Doos, John G. Batsakis, Rachel Bell, Stephanie Fofonoff, Richard Byers, E. Neely Atkinson, Charles W. Vaughan, Bela B. Toth, A. Kramer, I. W. Dimery, P. Skipper, S. Strong. 13-cis retinoic acid in the treatment of oral leukoplakia

Gideon Steinbach, Patrick M. Lynch, Robin K. S. Phillips, Marina H. Wallace, Ernest Hawk, Gary B. Gordon, Naoki Wakabayashi, Brian Saunders, Yu Shen, Takashi Fujimura, Li-Kuo Su, Bernard Levin. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

Nadir Arber, Craig J. Eagle, Julius Spicak, István Rácz, Petr Dite, Jan Hajer, Miroslav Zavoral, Maria J. Lechuga, Paola Gerletti, Jie Tang, Rebecca B. Rosenstein, Katie Macdonald, Pritha Bhadra, Robert Fowler, Janet Wittes, Ann G. Zauber, Scott D. Solomon, Bernard Levin, for the PreSAP Trial Investigators. A randomized controlled trial of celecoxib for the prevention of colorectal sporadic adenomatous polyps (PreSAP)

Scott D. Solomon, Marc A. Pfeffer, John J. V. McMurray, Rob Fowler, Peter Finn, Bernard Levin, Craig Eagle, Ernest Hawk, Mariajosé Lechuga, Ann G. Zauber, Monica M. Bertagnolli, Nadir Arber, Janet Wittes, for the APC and PreSAP Trial Investigators. Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas

Bernard Fisher, Joseph P. Costantino, D. Lawrence Wickerham, Carol K. Redmond, Maureen Kavanah, Walter M. Cronin, Victor Vogel, André Robidoux, Nikolay Dimitrov, James Atkins, Mary Daly, Samuel Wieand, Elizabeth Tan-Chiu, Leslie Ford, Norman Wolmark. Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

Bernard Fisher, Joseph P. Costantino, D. Lawrence Wickerham, Reena S. Cecchini, Walter M. Cronin, Andre Robidoux, Therese B. Bevers, Maureen T. Kavanah, James N. Atkins, Richard G. Margolese, Carolyn D. Runowicz, Joan M. James, Leslie G. Ford, Norman Wolmark. Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

Victor G. Vogel, Joseph P. Costantino, D. Lawrence Wickerham, Walter M. Cronin, Reena S. Cecchini, James N. Atkins, Therese B. Bevers, Louis Fehrenbacher, Eduardo R. Pajon, Jr., James L. Wade III, André Robidoux, Richard G. Margolese, Joan James, Scott M. Lippman, Carolyn D. Runowicz, Patricia A. Ganz, Steven E. Reis, Worta McCaskill-Stevens, Leslie G. Ford, V. Craig Jordan, Norman Wolmark for the National Surgical Adjuvant Breast and Bowel Project (NSABP). Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP study of tamoxifen and raloxifene (STAR) P-2 Trial

Paul M. Cinciripini, Janice Y. Tsoh, David W. Wetter, Cho Lam, Carl de Moor, Lynn Cinciripini, Walter Baile, Cheryl Anderson, John D. Minna. Combined effects of venlafaxine, nicotine replacement, and brief counseling on smoking cessation

Xifeng Wu, Karen Suchanek Hudmon, Michelle A. Detry, Robert M. Chamberlain, Margaret R. Spitz. D2 dopamine receptor gene polymorphisms among African-Americans and Mexican-Americans: A lung cancer case-control study

Margaret R. Spitz, Huihui Shi, Fang Yang, Karen Suchanek Hudmon, Hong Jiang, Robert M. Chamberlain, Christopher I. Amos, Ying Wan, Paul Cinciripini, Waun-Ki Hong, Xifeng Wu. Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients

Cancer Management and Quality of Life

Jeffrey W. Kwan, Russell W. Anderson. Pharmacists' knowledge of infusion devices

Evan M. Hersh, Gerald P. Bodey, B. A. Nies, Emil J Freireich. Causes of death in acute leukemia: A ten-year study of 414 patients

Freireich EJ. Effectiveness of platelet transfusion in leukemia and aplastic anemia. Transfusion. 1966;6:50-54.

Emil J Freireich, George Judson, Robert H. Levin. Separation and collection of leukocytes

Robert H. Levin, Jacqueline Whang, Paul P. Carbone, Emil J Freireich. Erythroid homograft following leukocyte transfusion in a patient with acute leukemia. I. Clinical studies and implications

Paul J. Schmidt, Mitsuo Yokoyama, Mary H. McGinniss, Robert H. Levin. Erythroid homograft following leukocyte transfusion in a patient with acute leukemia. II. Serologic and immunochemical studies

Kenneth B. McCredie, Evan M. Hersh, Emil J Freireich. Cells capable of colony formation in the peripheral blood of man

Gerald P. Bodey, Emil J Freireich, Emil Frei III. Studies of patients in a laminar air flow unit

Gerald P. Bodey, Edmund A. Gehan, Emil J Freireich, Emil Frei III. Protected environment - prophylactic antibiotic program in chemotherapy of acute leukemia

Gerald P. Bodey, Bent Rosenbaum. Effect of prophylactic measures on the microbial flora of patients in protected environment units

Mary Ann Weiser, Maria E. Cabanillas, Marina Konopleva, Deborah A. Thomas, Sherry A. Pierce, Carmen P. Escalante, Hagop M. Kantarjian, Susan M. O'Brien. Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen

Karin M. E. Hahn, Peter H. Johnson, Nancy Gordon, Henry Kuerer, Lavinia Middleton, Mildred Ramirez, Wei Yang, George Perkins, Gabriel N. Hortobagyi, Richard L. Theriault. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero

Rabih O. Darouiche, Issam I. Raad, Stephen O. Heard, John I. Thornby, Olivier C. Wenker, Andrea Gabrielli, Johannes Berg, Nancy Khardori, Hend Hanna, Ray Hachem, Richard L. Harris, Glen Mayhall, for The Catheter Study Group. A comparison of two antimicrobial-impregnated central venous catheters

Hend Hanna, Robert Benjamin, Ioannis Chatzinikolaou, Badie Alakech, Deborah Richardson, Paul Mansfield, Tanya Dvorak, Mark F. Munsell, Rabih Darouiche, Hagop M. Kantarjian, Issam Raad. Long-term silicone central venous catheters impregnated with minocycline and rifampin decrease rates of catheter-related bloodstream infection in cancer patients: A prospective randomized clinical trial

Rabih O. Darouiche, David H. Berger, Nancy Khardori, Claudia S. Robertson, Matthew J. Wall, Jr., Michael H. Metzler, Seema Shah, Mohammad D. Mansouri, Colleen Cerra-Stewart, James Versalovic, Michael J. Reardon, Issam I. Raad. Comparison of antimicrobial impregnation with tunneling of long-term central venous catheters: A randomized controlled trial

Gabriel Lopez-Berestein, Victor Fainstein, Roy Hopfer, Komal Mehta, Maryrose P. Sullivan, Michael Keating, Michael G. Rosenblum, Rohit Mehta, Mario Luna, Evan M. Hersh, J. Reuben, R. L. Juliano, Gerald P. Bodey. Liposomal amphotericin B for the treatment of systemic fungal infections in patients with cancer: A preliminary study

Michael Frumovitz, Charlotte C. Sun, Leslie R. Schover, Mark F. Munsell, Anuja Jhingran, J. Taylor Wharton, Patricia Eifel, Therese B. Bevers, Charles F. Levenback, David M. Gershenson, Diane C. Bodurka. Quality of life and sexual functioning in cervical cancer survivors

Dina Lev, Dhanasekaran Kotilingam, Caimiao Wei, Matthew T. Ballo, Gunar K. Zagars, Peter W. T. Pisters, Alexander A. Lazar, Shreyaskumar R. Patel, Robert S. Benjamin, Raphael E. Pollock. Optimizing treatment of desmoid tumors

Waun-Ki Hong. The Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer

Lara Bashoura, Sachin Gupta, Amit Jain, Daniel R. Couriel, Krishna V. Komanduri, Georgie A. Eapen, Amar Safdar, Kristine R. Broglio, Roberto Adachi, Burton F. Dickey. Inhaled corticosteroids stabilize constrictive bronchiolitis after hematopoietic stem cell transplantation

Sidney Wallace, Chusilp Charnsangavej, C. Humberto Carrasco, William Bechtel, Kenneth C. Wright, Cesare Gianturco. Percutaneous transcatheter infusion and infarction in the treatment of human cancer: Part I

Sidney Wallace, C. Humberto Carrasco, Chusilp Charnsangavej, Y. Y. Lee, Kenneth C. Wright, Cesare Gianturco. Percutaneous transcatheter infusion and infarction in the treatment of human cancer: Part II

Sidney Wallace, C. Humberto Carrasco, Chusilp Charnsangavej, William R. Richli, Kenneth C. Wright, Cesare Gianturco. Hepatic artery infusion and chemoembolization in the management of liver metastases

Michael J. Wallace, Chusilp Charnsangavej, Kenji Ogawa, C. Humberto Carrasco, Kenneth C. Wright, Robert McKenna, Marion McMurtrey, Cesare Gianturco. Tracheobronchial tree: Expandable metallic stents used in experimental and clinical applications. Work in progress

Lorenzo Cohen, Carle Warneke, Rachel T. Fouladi, M. Alma Rodriguez, Alejandro Chaoul-Reich. Psychological adjustment and sleep quality in a randomized trial of the effects of a Tibetan yoga intervention in patients with lymphoma

Victorio Rodriguez, Dorothy Stewart, Gerald P. Bodey. Gentamicin sulfate distribution in body fluids

Gerald P. Bodey, E. Middleman, Theera Umsawasdi, Victorio Rodriguez. Intravenous gentamicin therapy for infections in patients with cancer

Innovations in Therapy

Clinical Trial Design

Donald A. Berry. Bayesian clinical trials

Chemotherapy

Richard Champlin, Issa Khouri, Avichai Shimoni, James Gajewski, Steven Kornblau, Jeffrey Molldrem, Naoto Ueno, Sergio Giralt, Paolo Anderlini. Harnessing graft-versus-malignancy: Non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapy

Sergio Giralt, Elihu Estey, Maher Albitar, Koen van Besien, Gabriela Rondón, Paolo Anderlini, Susan O'Brien, Issa Khouri, James Gajewski, Rakesh Mehra, David Claxton, Borje Andersson, Miloslav Beran, Donna Przepiorka, Charles Koller, Steve Kornblau, Martin Körbling, Michael Keating, Hagop M. Kantarjian, Richard Champlin. Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: Harnessing graft-versus-leukemia without myeloablative therapy

Issa F. Khouri, Michael Keating, Martin Körbling, Donna Przepiorka, Paolo Anderlini, Susan O'Brien, Sergio Giralt, Cindy Ippoliti, Brigite von Wolff, James Gajewski, Michelle Donato, David Claxton, Naoto Ueno, Borje Andersson, Adrian Gee, Richard Champlin. Transplant lite: Induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor cell transplantation as treatment for lymphoid malignancies

Gabriel N. Hortobagyi, W. Spanos, Eleanor D. Montague, Aman U. Buzdar, H. Y. Yap, George R. Blumenschein. Treatment of locoregionally advanced breast cancer with surgery, radiotherapy and combination chemoimmunotherapy

Gabriel N. Hortobagyi, George R. Blumenschein, W. Spanos, Eleanor D. Montague, Aman U. Buzdar, H. Y. Yap. Multimodal treatment of locoregionally advanced breast cancer

Jack A. Roth, Frank Fossella, Ritsuko Komaki, M. Bernadette Ryan, J. B. Putnam, Jr., Jin Soo Lee, Hari Dhingra, Louis De Caro, Marvin Chasen, Malcoln McGavran, E. Neely Atkinson, Waun-Ki Hong. A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer

Francis R. Spitz, James L. Abbruzzese, Jeffrey E. Lee, Peter W. T. Pisters, Andrew M. Lowy, Claudio J. Fenoglio, Karen R. Cleary, Nora A. Janjan, Mary S. Goswitz, Tyvin A. Rich, Douglas B. Evans. Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas

Peter W. T. Pisters, James L. Abbruzzese, Nora A. Janjan, Karen R. Cleary, Chusilp Charnsangavej, Mary S. Goswitz, Tyvin A. Rich, Isaac Raijman, Robert A. Wolff, Renato Lenzi, Jeffrey E. Lee, Douglas B. Evans. Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy and intraoperative radiation therapy for resectable pancreatic adenocarcinoma

M. P. Sullivan, W. W. Sutow, A. Cangir, G. Taylor. Vincristine sulfate in management of Wilms' tumor. Replacement of preoperative irradiation by chemotherapy

Jeffrey A. Gottlieb, Jordan U. Gutterman, Kenneth B. McCredie, Victorio Rodriguez, Emil Frei III. Chemotherapy of malignant lymphoma with Adriamycin

E. M. McKelvey, Jeffrey A. Gottlieb, H. E. Wilson, A. Haut, R. W. Talley, R. Stephens, M. Lane M, J. F. Gamble, S. E. Jones, P. N. Grozea, Jordan U. Gutterman, C. Coltman, T. E. Moon. Hydroxyldaunomycin (Adriamycin) combination chemotherapy in malignant lymphoma

Frankie Ann Holmes, Ronald S. Walters, Richard L. Theriault, Aman U. Buzdar, Debra K. Frye, Gabriel N. Hortobagyi, Arthur D. Forman, Lesley K. Newton, Martin N. Raber. Phase II trial of Taxol, an active drug in the treatment of metastatic breast cancer

Jeffrey A. Gottlieb, Jordan U. Gutterman, Kenneth B. McCredie, Victorio Rodriguez, Emil Frei III. Chemotherapy of malignant lymphoma with Adriamycin

Aman U. Buzdar, Jordan U. Gutterman, George R. Blumenschein, Gabriel N. Hortobagyi, Charles K. Tashima, Terry L. Smith, Evan M. Hersh, Emil J Freireich, Edmund A. Gehan. Intensive postoperative chemoimmunotherapy for patients with stage II and stage III breast cancer

Jeffrey A. Gottlieb, L. H. Baker, J. M. Quagliana, J. K. Luce, J. P. Whitecar, J. G. Sinkovics, S. E. Rivkin, R. Brownlee, Emil Frei III. Chemotherapy of sarcomas with a combination of Adriamycin and dimethyl triazeno imidazole carboxamide

W. K. Alfred Yung, Michael D. Prados, Ricardo Yaya-Tur, Steven S. Rosenfeld, Michael Brada, Henry S. Friedman, Robert Albright, Jeffrey Olson, Susan M. Chang, Alison M. O'Neill, Allan H. Friedman, Janet Bruner, Nancy Yue, Margaret Dugan, Sara Zaknoen, Victor A. Levin, for the Temodal Brain Tumor Group. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse

I. Fokt, C. Conrad, T. Madden, A. W. Yung, F. F. Lang, N. Thapar, W. Priebe. The discovery and development of blood-brain barrier (BBB) penetrating anthracyclines for the treatment of brain tumors. Proceedings of AACR-NCI-EORTC International Conference. Philadelphia, PA. A199, page 106, 2005

W. Priebe, T. Madden, I. Fokt, M. Johansen, C. Conrad. Modular design of DNA binding agents capable of penetrating blood-brain barrier and targeting brain tumors. American Association for Cancer Research-American Chemical Society Joint Conference. Chemistry in Cancer Research: A Vital Partnership. San Diego, CA, February 4–8, 2007

Bharat B. Aggarwal, Anushree Kumar, Alok C. Bharti. Anticancer potential of curcumin: Preclinical and clinical studies [review]

Hagop M. Kantarjian, Varsha Gandhi, Peter Kozuch, Stefan Faderl, Francis Giles, Jorge E. Cortes, Susan O'Brien, Nuhad Ibrahim, Fadlo Khuri, Min Du, Mary Beth Rios, Sima Jeha, Peter McLaughlin, William Plunkett, Michael Keating. Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers

Hagop M. Kantarjian, Varsha Gandhi, Jorge E. Cortes, Srdan Verstovsek, Min Du, Guillermo Garcia-Manero, Francis Giles, Stefan Faderl, Susan O'Brien, Sima Jeha, Jan Davis, Zeev Shaked, Adam Craig, Michael Keating, William Plunkett, Emil J Freireich. Phase II clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia

Sima Jeha, Varsha Gandhi, Ka Wah Chan, Lisa McDonald, Irma Ramirez, Renee Madden, Michael Rytting, Mark Brandt, Michael Keating, William Plunkett, Hagop M. Kantarjian. Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia

Stefan Faderl, Varsha Gandhi, Susan O'Brien, Peter Bonate, Jorge E. Cortes, Elihu Estey, Miloslav Beran, William Wierda, Guillermo Garcia-Manero, Alessandra Ferrajoli, Zeev Estrov, Francis J. Giles, Min Du, Monica Kwari, Michael Keating, William Plunkett, Hagop M. Kantarjian. Results of a phase I-II study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias

Sima Jeha, Hagop M. Kantarjian. Clofarabine for the treatment of acute lymphoblastic leukemia

Borje S. Andersson, James Gajewski, Michelle Donato, Sergio Giralt, Victor Gian, John R. Wingard, Stefano Tarantolo, Hugo Fernandez, Wendy W. Hu, Karl Blume, Ashwin Kashyap, Stephen J. Forman, Richard E. Champlin. Allogeneic stem cell transplantation (BMT) for AML and MDS following IV busulfan and cyclophosphamide (IV BuCY)

Waldemar Priebe, Roman Perez-Soler. Design tumor targeting of anthracyclines able to overcome multidrug resistance: A double-advantage approach

Roman Perez-Soler, Yi-He Ling, Yiyu Zou, Waldemar Priebe. Cellular pharmacology of the partially non-cross-resistant anthracycline Annamycin entrapped in liposomes in KB and KB-V1 cells

Ugo Consoli, Waldemar Priebe, Yi-He Ling, Radha Mahadevia, Mark Griffin, Shourong Zhao, Roman Perez-Soler, Michael Andreeff. The novel anthracycline Annamycin is not affected by P-glycoprotein-related multidrug resistance: Comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines

James L. Abbruzzese, Ralf Grunewald, Earle A. Weeks, Diane Gravel, Theresa Adams, Billie Nowak, Shin Mineishi, Peter Tarassoff, Winston Satterlee, Martin N. Raber, William Plunkett. A phase I clinical, plasma and cellular pharmacology study of gemcitabine

William K. Murphy, Frank V. Fossella, Rodger J. Winn, Dong M. Shin, H. E. Hynes, Howard M. Gross, Enrique Davilla, Joseph Leimert, Hari Dhingra, Martin N. Raber, Irwin H. Krakoff, Waun-Ki Hong. Phase II study of taxol in patients with untreated advanced non-small-cell lung cancer

Combination Therapies

Mitchell Morris, Patricia J. Eifel, Jiandong Lu, Perry W. Grigsby, Charles Levenback, Randy E. Stevens, Marvin Rotman, David M. Gershenson, David G. Mutch. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer

Aman U. Buzdar, Nuhad K. Ibrahim, Deborah Francis, Daniel J. Booser, Eva S. Thomas, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Banu K. Arun, Sharon H. Giordano, Massimo Cristofanilli, Debra K. Frye, Terry L. Smith, Kelly K. Hunt, Sonja E. Singletary, Aysegul A. Sahin, Michael S. Ewer, Thomas A. Buchholz, Donald Berry, Gabriel N. Hortobagyi. Significantly higher pathological complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer, paclitaxel and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer

Aman U. Buzdar, Vicente Valero, Nuhad K. Ibrahim, Deborah Francis, Kristine R. Broglio, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Sonja E. Singletary, Kelly K. Hunt, Aysegul A. Sahin, Francisco Esteva, William F. Symmans, Michael S. Ewer, Thomas A. Buchholz, Gabriel N. Hortobagyi. Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: An update of the initial randomized study population and data of additional patients treated with the same regimen

Charles H. Yang, Massimo Cristofanilli. Systemic treatments for inflammatory breast cancer

Jordan U. Gutterman, Juan O. Cardenas, George R. Blumenschein, Gabriel N. Hortobagyi, Michael A. Burgess, Robert B. Livingston, Giora M. Mavligit, Emil J Freireich, Jeffrey A. Gottlieb, Evan M. Hersh. Chemoimmunotherapy of advanced breast cancer: Prolongation of remission and survival with BCG

Aman U. Buzdar, Jordan U. Gutterman, George R. Blumenschein, Gabriel N. Hortobagyi, Charles K. Tashima, Terry L. Smith, Evan M. Hersh, Emil J Freireich, Edmund A. Gehan. Intensive postoperative chemoimmunotherapy for patients with stage II and stage III breast cancer

Aman U. Buzdar, George R. Blumenschein, Jordan U. Gutterman, Charles K. Tashima, Gabriel N. Hortobagyi, Terry L. Smith, Luis T. Campos, Warren L. Wheeler, Evan M. Hersh, Emil J Freireich, Edmund A. Gehan. Postoperative adjuvant chemotherapy with 5-fluorouracil, doxorubicin, cyclophosphamide and BCG: A follow-up report

Gabriel N. Hortobagyi, Richard L. Theriault, Lester Porter, Douglas Blayney, Allan Lipton, Clive Sinoff, Helen Wheeler, Joseph F. Simeone, John Seaman, Robert D. Knight, Maika Heffernan, Dirk J. Reitsma, Ian Kennedy, Simon G. Allan, Kathleen Mellars, for The Protocol 19 Aredia Breast Cancer Study Group. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone lesions

Gabriel N. Hortobagyi, Richard L. Theriault, Allan Lipton, Lester Porter, Douglas Blayney, Clive Sinoff, Helen Wheeler, Joseph F. Simeone, John J. Seaman, Robert D. Knight, Maika Heffernan, Kathleen Mellars, Dirk J. Reitsma for The Protocol 19 Aredia Breast Cancer Study Group. Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate

Richard L. Theriault, Allan Lipton, Gabriel N. Hortobagyi, Richard Leff, Stefan Glück, John F. Stewart, Sean Costello, Ian Kennedy, Joseph Simeone, John J. Seaman, Robert D. Knight, Kathleen Mellars, Maika Heffernan, Dirk J. Reitsma, for The Protocol 18 Aredia Breast Cancer Study Group. Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial

Shi-Ming Tu, Randall E. Millikan, Bayabel Mengistu, Ebrahim S. Delpassand, Robert J. Amato, Lance C. Pagliaro, Danai Daliani, Christos N. Papandreou, Terry L. Smith, Jeri Kim, Donald A. Podoloff, Christopher J. Logothetis. Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: A randomised phase II trial

Michael J. Keating, Susan O'Brien, Susan Lerner, William G. Wierda, Hagop M. Kantarjian. Chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) improves complete response (CR), remission duration and survival as initial therapy of chronic lymphocytic leukemia (CLL)

Michael J. Keating, Hagop M. Kantarjian, Moshe Talpaz, John Redman, Charles Koller, Barthel Barlogie, William Velasquez, William Plunkett, Emil J Freireich, Kenneth B. McCredie. Fludarabine: A new agent with major activity against chronic lymphocytic leukemia

Luka Milas, Kathy Mason, Nancy Hunter, Sven Petersen, Michitaka Yamakawa, Kian Ang, John Mendelsohn, Zhen Fan. In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody

Sachiko Nasu, K. Kian Ang, Zhen Fan, Luka Milas. C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability

K. Kian Ang, Brian A. Berkey, Xiaoyu Tu, Hua-Zhong Zhang, Ruth Katz, Elizabeth H. Hammond, Karen K. Fu, Luka Milas. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma

H. Prast, M. Heistracher, A. Philippu. In vivo modulation of the histamine release in the hypothalamus by adrenoreceptor agonists and antagonists

New Targeted Therapies

Hagop M. Kantarjian, Moshe Talpaz, Susan O'Brien, Terry L. Smith, Francis J. Giles, Stefan Faderl, Deborah A. Thomas, Guillermo Garcia-Manero, Jean-Pierre J. Issa, Michael Andreeff, Steven M. Kornblau, Charles Koller, Milosav Beran, Michael Keating, Mary Beth Rios, Jenny Shan, Debra Resta, Renaud Capdeville, Kimberly Hayes, Maher Albitar, Emil J Freireich, Jorge E. Cortes. Imatinib mesylate for Philadelphia chromosome- positive, chronic-phase myeloid leukemia after failure of interferon-alpha: Follow-up results

Hagop M. Kantarjian, Jorge E. Cortes, Susan O'Brien, Francis Giles, Guillermo Garcia-Manero, Stefan Faderl, Deborah Thomas, Sima Jeha, Mary Beth Rios, Laurie Letvak, Kathy Bochinski, Ralph Arlinghaus, Moshe Talpaz. Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses

Hagop M. Kantarjian, Moshe Talpaz, Susan O'Brien, Francis Giles, Guillermo Garcia-Manero, Stefan Faderl, Deborah Thomas, Jianqin Shan, Mary Beth Rios, Jorge E. Cortes. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia

Hagop M. Kantarjian, Moshe Talpaz, Susan O'Brien, Guillermo Garcia-Manero, Srdan Verstovsek, Francis Giles, Mary Beth Rios, Jianqin Shan, Laurie Letvak, Deborah Thomas, Stefan Faderl, Alessandra Ferrajoli, Jorge E. Cortes. High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia

Hagop M. Kantarjian, Francis Giles, Lydia Wunderle, Kapil Bhalla, Susan O'Brien, Barbara Wassmann, Chiaki Tanaka, Paul Manley, Patricia Rae, William Mietlowski, Kathy Bochinski, Andreas Hochhaus, James D. Griffin, Dieter Hoelzer, Maher Albitar, Margaret Dugan, Jorge E. Cortes, Leila Alland, Oliver G. Ottmann. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

Jean-Pierre J. Issa, Guillermo Garcia-Manero, Francis J. Giles, Rajan Mannari, Deborah Thomas, Stefan Faderl, Emel Bayar, John Lyons, Craig S. Rosenfeld, Jorge E. Cortes, Hagop M. Kantarjian. Phase I study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

Allen S. Yang, Ketan D. Doshi, Sang-Woon Choi, Joel B. Mason, Rajan K. Mannari, Vazganush Gharybian, Rene Luna, Asif Rashid, Lanlan Shen, Marcos R. H. Estecio, Hagop M. Kantarjian, Guillermo Garcia-Manero, Jean-Pierre J. Issa. DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia

Hagop M. Kantarjian, Yasuhiro Oki, Guillermo Garcia-Manero, Xuelin Huang, Susan O'Brien, Jorge E. Cortes, Stefan Faderl, Carlos Bueso-Ramos, Farhad Ravandi, Zeev Estrov, Alessandra Ferrajoli, William Wierda, Jianqin Shan, Jan Davis, Francis Giles, Hussain I. Saba, Jean-Pierre J. Issa. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia

Immunologic Therapies

Razelle Kurzrock, Michael G. Rosenblum, Stephen A. Sherwin, Adan Rios, Moshe Talpaz, Jorge R. Quesada, Jordan U. Gutterman. Pharmacokinetics, single-dose tolerance, and biological activity of recombinant gamma-interferon in cancer patients

Jordan U. Gutterman, S. Fine, Jorge Quesada, S. J. Horning, J. F. Levine, Raymond Alexanian, L. Bernhardt, M. Kramer, H. Spiegel, W. Colburn, P. Trown, T. Merigan, Z. Dziewanowski. Recombinant leukocyte A interferon: Pharmacokinetics, single-dose tolerance, and biologic effects in cancer patients

Jordan U. Gutterman, George R. Blumenschein, Raymond Alexanian, H. Y. Yap, Aman U. Buzdar, F. Cabanillas, Gabriel N. Hortobagyi, Evan M. Hersh, S. L. Rasmussen, M. Harmon, M. Kramer, S. Pestka. Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma

Jeffrey J. Molldrem, Peter P. Lee, Changqing Wang, Kyrie Felio, Hagop M. Kantarjian, Richard E. Champlin, Mark M. Davis. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

Sylvie Rusakiewicz, Shreya Kant, Gregory Lizee, Brian Rabinovich, Eric Wieder, Sijie Lu, Patrick Hwu, Jeffrey J. Molldrem. CD8 T cells with high avidity TCR-ab specific for serine protease self-determinants for use in adoptive immunotherapy of human leukemia

Radiation Therapy

L. G. Grimmett. A 1000-Curie Cobalt-60 Irradiator

L. G. Grimmett, H. D. Kerman, M. Brucer, Gilbert H. Fletcher, J. E. Richardson. Design and construction of a multicurie cobalt teletherapy unit

Gilbert H. Fletcher, Eleanor D. Montague, Alvah J. Nelson III. Combination of conservative surgery and irradiation for cancer of the breast

B. Fisher, Eleanor D. Montague, C. Redmond, B. Barton, D. Borland, E. R. Fisher, M. Deutsch, G. Schwarz, R. Margolese, W. Donegan, H. Volk, C. Konvolinka, B. Gardner, I. Cohn, Jr., G. Lesnick, A. B. Cruz, W. Lawrence, T. Nealon, H. Butcher, R. Lawton. Comparison of radical mastectomy with alternative treatments for primary breast cancer: A first report of results from a prospective randomized clinical trial

Eleanor D. Montague, A. E. Gutierrez, J. L. Barker, N. D. Tapley, Gilbert H. Fletcher. Conservation surgery and irradiation for the treatment of favorable breast cancer

Kenneth R. Hogstrom, Michael D. Mills, Peter R. Almond. Electron beam dose calculations

Kenneth R. Hogstrom, Michael D. Mills, J. A. Meyer, J. R. Palta, D. E. Mellenberg, R. T. Meoz, R. S. Fields. Dosimetric evaluation of a pencil-beam algorithm for electrons employing a two-dimensional heterogeneity correction

Almon S. Shiu, Hanne M. Kooy, James R. Ewton, Samuel S. Tung, Jeremy Wong, Kyle Antes, Moshe H. Maor. Comparison of miniature multileaf collimation (MMLC) with circular collimation for stereotactic treatment

Brent C. Parker, Almon S. Shiu, Moshe H. Maor, Frederick F. Lang, H. Helen Liu, R. Allen White, John A. Antolak. PTV margin determination in conformal SRT of intracranial lesions

Almon S. Shiu, B. Parker, J. Ye, J. Lii. An integrated treatment delivery system for CSRS and CSRT and clinical applications

Eric L. Chang, Almon S. Shiu, Ming-Fwu Lii, Laurence D. Rhines, Ehud Mendel, Anita Mahajan, Jeffrey S. Weinberg, Leni A. Mathews, Barry W. Brown, Moshe H. Maor, James D. Cox. Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases

Almon S. Shiu, Eric L. Chang, Jin-Song Ye, Ming-Fwu Lii, Laurence D. Rhines, Ehud Mendel, Jeffrey Weinberg, Sanjay Singh, Moshe H. Maor, Radhe Mohan, James D. Cox. Near simultaneous computed tomography image-guided stereotactic spinal radiotherapy: An emerging paradigm for achieving true stereotaxy

Adam S. Garden, William H. Morrison, Pei-Fong Wong, Sam S. Tung, David I. Rosenthal, Lei Dong, Brian Mason, George H. Perkins, K. Kian Ang. Disease-control rates following intensity-modulated radiation therapy for small primary oropharyngeal carcinoma

Gokhan Ozyigit, Thomas Yang, K. S. Clifford Chao. Intensity-modulated radiation therapy for head and neck cancer

Ulrich Hermanto, Erik K. Frija, MingFwu J. Lii, Eric L. Chang, Anita Mahajan, Shiao Y. Woo. Intensity-modulated radiotherapy (IMRT) and conventional three-dimensional conformal radiotherapy for high-grade gliomas: Does IMRT increase the integral dose to normal brain?

Surgery

Steven J. Kronowitz, Henry M. Kuerer. Advances and surgical decision-making for breast reconstruction

Steven J. Kronowitz, Jules A. Feledy, Kelly K. Hunt, Henry M. Kuerer, Adel Youssef, Cindy A. Koutz, Geoffrey L. Robb. Determining the optimal approach to breast reconstruction after partial mastectomy

Steven J. Kronowitz, Geoffrey L. Robb, Adel Youssef, Gregory Reece, Shih-Hsin Chang, Cynthia A. Koutz, Roy L. Ng, Joan E. Lipa, Michael J. Miller. Optimizing autologous breast reconstruction in thin patients

Steven J. Kronowitz, David W. Chang, Geoffrey L. Robb, Kelly K. Hunt, Fred C. Ames, Merrick I. Ross, S. Eva Singletary, W. Fraser Symmans, Stephen S. Kroll, Henry M. Kuerer. Implications of axillary sentinel lymph node biopsy in immediate autologous breast reconstruction

Chandrajit P. Raut, Kelly K. Hunt, Jeri S. Akins, M. Denise Daley, Merrick I. Ross, S. Eva Singletary, Gailen D. Marshall, Jr., Funda Meric-Bernstam, Gildy Babiera, Barry W. Feig, Frederick C. Ames, Henry M. Kuerer. Incidence of anaphylactoid reactions to isosulfan blue dye during breast carcinoma lymphatic mapping in patients treated with preoperative prophylaxis: Results of a surgical prospective clinical practice protocol

Chandrajit P. Raut, M. Denise Daley, Kelly K. Hunt, Jeri Akins, Merrick I. Ross, S. Eva Singletary, Gailen D. Marshall, Jr., Funda Meric-Bernstam, Gildy Babiera, Barry W. Feig, Frederick C. Ames, Henry M. Kuerer. Anaphylactoid reactions to isosulfan blue dye during breast cancer lymphatic mapping in patients given preoperative prophylaxis

Peirong Yu, Jan S. Lewin, Gregory P. Reece, Geoffrey L. Robb. Comparison of clinical and functional outcomes and hospital costs following pharyngoesophageal reconstruction with the anterolateral thigh free flap versus the jejunal flap

Peirong Yu, Geoffrey L. Robb. Pharyngoesophageal reconstruction with the anterolateral thigh flap: A clinical and functional outcomes study

Rajesh K. Bindal, Raymond Sawaya, Milam E. Leavens, J. J. Lee. Surgical treatment of multiple brain metastases