MDACC Study Summary 2004-0039 (Archived)

Study Summary
No. 2004-0039:.......Colorectal......Susan Peterson......Behavioral Science

Study Summary Title



Study Summary Number:	2004-0039

Study Title:	Colorectal Cancer (CRC) Screening in First-Degree Relatives of Hispanic CRC Patients

Physician

New Patient Referral



Name:	Susan Peterson	Patients Call:	800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)

Dept:	Behavioral Science	Referring MD Call:	800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)

Phone:	713-792-8267 Contact us about clinical trials

General Information



Disease Group:	Colorectal	Supported By:	N/A

Phase of Study:	N/A	Return Visit:	N/A

Treatment Agents:	None	Home Care:	N/A

Treatment Loc:	Only at MDACC

Estimated Length of Stay in Houston:	N/A


Description/ Intervention:	The goal of this research study is to learn about the knowledge, beliefs, and attitudes that people have toward screening for colorectal cancer. Another goal is to study how families communicate about colorectal cancer risk and colorectal cancer screening, with each other and with health care providers.

Study Objectives / Outcomes

The primary goal of this study is to conduct the first phase of basic, descriptive research regarding colorectal cancer screening adherence and family communication about colorectal cancer (CRC) risk and screening among Hispanic CRC patients and their first-degree relatives. This will be accomplished through a series of semi-structured, qualitative interviews conducted with key informants (comprised of health care and other professionals who are knowledgeable about issues impacting cancer prevention behaviors among Hispanics), CRC patients, and the first degree relatives (FDRs) of those patients.

The aims of this study include:
1) To evaluate knowledge, beliefs, attitudes and values that influence perceptions and utilization of colorectal cancer screening (CRCS) among first-degree relatives of Hispanic CRC patients.
2) To assess factors influencing Hispanic CRC patients' communication of CRC risk and screening information to their FDRs.

A secondary goal of this study is to establish the feasibility of recruiting Hispanic CRC patients and their FDRs from the institutional patient database and/or MDACC clinics.

Data from this study will help fill the void of knowledge about factors associated with CRCS adherence among Hispanics who are at increased CRC risk because of their family history of the disease. This study will begin to explore a new area of investigation; namely, factors related to Hispanic CRC patients' willingness to discuss CRC risk and screening with their FDRs. Our findings will be directly applicable to the development of culturally relevant measures to assess CRCS behaviors and CRC risk communication within families. Ultimately, the long-term goal of this research is to develop family-based interventions aimed at improving dissemination of CRC risk and screening information and improving screening intentions among Hispanics, and ultimately increasing the suboptimal levels of screening currently observed in this population.

Study Status Information



Study Activation / Registration Date:	02/08/2005

IRB Review and Approval Date:	02/18/2004

Study Type:	Screening

Recruitment Status:	Terminated

Projected Accrual:	75

Enrollment Eligibility

If you do not meet the enrollment eligibility, there may be other treatment options for you. Please Contact the Referral Office for more information.

Inclusion Criteria:

1) Key Informants: Persons will be identified as potentially eligible key informants if they are: 1) members of the Houston Hispanic Health Coalition, or if they are identified through the Houston Hispanic Health Coalition as having professional expertise relevant to this study. 2) Able to speak English or Spanish. 3) Able to provide informed consent.

2) CRC Patients: Eligibility criteria include: 1) Living MDACC patients with a personal history of colorectal adenocarcinoma (diagnosed as local or regional disease), who are between the ages of 18 and 60 years, who are identified as Hispanic/Latino, and who have living first degree relatives (siblings or children) between the ages of 40 and 70. 2) Able to provide informed consent. Eligible persons may speak either English or Spanish.

3) First-degree relatives (FDRs): Eligibility criteria include: 1) First-degree relatives (siblings and children) of the MDACC CRC cancer patients who are recruited to this study, who are 40 to 70 years of age. 2) Able to provide informed consent. Eligible persons may speak either English or Spanish.

4) Note: As described in the above inclusion criteria, this protocol involves recruiting and interviewing of key informants, CRC patients, and eligible first-degree relatives (FDRs) of CRC patients for three phases of the study.

Exclusion Criteria:

1) CRC Patients: CRC patients will be excluded if they have a history of a known hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or inflammatory bowel disease (e.g., ulcerative colitis or Crohn's disease), or were diagnosed with distant metastases.

2) First degree relatives: FDRs of eligible CRC patients will be excluded if they have a history of a known hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or inflammatory bowel disease (e.g., ulcerative colitis or Crohn's disease), or have a personal history of cancer (except non-melanoma skin cancer) or polyps.

Links

Registration Number: NCT00838318
Study Information on Clinical Trials Registry (clinicaltrials.gov)