CLINICAL TRIAL SUMMARY

MDACC Study No:2004-0874 (clinicaltrials.gov NCT No: NCT00242502)
Title:A Phase II Study of the Combination of Avastin and Erlotinib in Patients with Unresectable Hepatocellular Carcinoma
Principal Investigator:Ahmed Kaseb
Treatment Agent:Avastin; Erlotinib
Study Status:Terminated
Study Description:The goal of this clinical research study is to learn if treatment with Avastin
combined with Tarceva (OSI-774/erlotinib hydrochloride) can help to slow the
growth of advanced liver cancer. The safety of this combination treatment
will also be studied.

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Disease Group:Gastrointestinal
Phase of Study:Phase II
Treatment Agents:Avastin
Erlotinib
Treatment Location:Only at MDACC
Estimated Length of Stay in Houston:Hospitalization is not required for this study.
Supported By:N/A
Return Visit:Patients must come to MDACC every two weeks for Avastin infusion.
Home Care:Patient will take erlotinib orally on a daily basis at home.
Study tests and evaluations will be performed at MDACC.


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Physician Name:Ahmed Kaseb
Dept:Gastrointestinal Medical Oncology
For Clinical Trial Enrollment:713-792-2828
For General Questions about Clinical Trials:800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)


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