|MDACC Study No:||2008-0276 (clinicaltrials.gov NCT No: NCT00965172)|
|Title:||A Phase II study to evaluate the preliminary efficacy assessment of Caphosol in patients with sarcoma receiving multicycle chemotherapy with doxorubicin and ifosfamide or cisplatin|
|Principal Investigator:||Saroj Vadhan-Raj|
|Treatment Agent:||Cisplatin; Doxorubicin; Filgrastim; Ifosfamide; Palifermin; Pegfilgrastim; Sodium Bicarbonate|
|Study Description:||The goal of this clinical research study is to find out if CaphosolŪ (calcium |
phosphate) mouthwash is more effective than a baking soda solution at
preventing and treating mucositis, in patients with sarcoma who are to be
treated with chemotherapy. The safety of this drug will also be studied.
Researchers also want to learn about the way calcium phosphate may affect
The goal of this clinical research study is to see if CaphosolŪ (calcium
phosphate) mouthwash is better than baking soda solution in patients with
sarcoma who are to be treated with chemotherapy . Caphosol will also be
studied to see if it lessens the incidence and severity of oral mucositis
(painful sores in the mouth).