MDACC Study Summary 2008-0308

Study Summary
No. 2008-0308:.......Aids......Damon Vidrine......Behavioral Science

Study Summary Title



Study Summary Number:	2008-0308

Study Title:	The Influence of HIV Disease Events/Stages on Smoking Attitudes and Behaviors

Physician

New Patient Referral



Name:	Damon Vidrine	Patients Call:	800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)

Dept:	Behavioral Science	Referring MD Call:	800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)

Phone:	713-792-8270 Contact us about clinical trials

General Information



Disease Group:	Aids	Supported By:	National Cancer Institute

Phase of Study:	N/A	Return Visit:	Participants will not be seen at MDACC.

Treatment Agents:	None	Home Care:	NA

Treatment Loc:	Only outside MDACC at one or more Collaborating Sites or Institutions

Estimated Length of Stay in Houston:	Hospitalization is not required.


Description/ Intervention:	The goal of this research study is to learn more about the relationship between HIV disease stages and smoking behavior. Researchers also want to learn if HIV-related events, such as changes in treatment and/or the diagnosis of an HIV-related disease, influence attitudes and/or behavior about cigarette smoking.

Study Objectives / Outcomes

The primary specific aims are to:

1. Assess the relationship between HIV disease events/stages (i.e.,

HIV-care initiation, stable disease, and progressive disease) and smoking outcomes (i.e., intention to quit, number of quit attempts, and cessation outcomes).

Hypothesis 1.

HIV disease events/stages will be associated with smoking outcomes.The strongest intentions to quit smoking and highest rates of smoking cessation will be observed at the time of the initiation of HIV-care, followed by points in time when the disease is actively progressing. The weakest intentions to quit and lowest cessation rates will be observed during periods of stable HIV disease.

2. Evaluate perceived impact of HIV as a potential mediator of the association between disease event/stage and smoking outcomes.

Hypothesis 2.

Perceived impact of HIV will significantly mediate the relationship between disease events/stages and smoking outcomes.

3. Evaluate potential mediators (i.e., attitudes about smoking) and moderators (i.e., perceived control and social norms) of the relationship between perceived impact of HIV-disease and smoking outcomes.

Hypothesis 3a

. Attitudes about smoking (i.e., quit motivation, outcome expectancies, and risk perceptions) will significantly mediate the relationship between perceived impact of HIV and smoking outcomes (i.e., intentions to quit and cessation outcomes).

Hypothesis 3b

. Subjective norms and perceived control over quitting smoking will be significant moderators of the relationship between perceived impact of HIV and smoking outcomes.

Study Status Information



Study Activation / Registration Date:	05/28/2009

IRB Review and Approval Date:	05/28/2009

Study Type:	Behavioral

Recruitment Status:	Open

Projected Accrual:	450

Enrollment Eligibility

If you do not meet the enrollment eligibility, there may be other treatment options for you. Please Contact the Referral Office for more information.

Inclusion Criteria:

1) New patient receiving care for HIV/AIDS at Thomas Street Health Center

2) 18 years of age or older

3) Self-reported current smoker at the time of enrollment (smoked at least 100 cigarettes in lifetime and smoking every day or most days)

4) Able to provide written informed consent to participate

5) English or Spanish speaking

Exclusion Criteria:

1) Physician deemed ineligibility based on medical (HIV related or other condition) or psychiatric condition

Links

Registration Number: Not Applicable Clinical Trial