CLINICAL TRIAL SUMMARY

MDACC Study No:2008-0318 (clinicaltrials.gov NCT No: NCT00895960)
Title:Phase I/II Trial of Dasatinib (Sprycel) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Newly-Diagnosed Glioblastoma
Principal Investigator:John DeGroot
Treatment Agent:Dasatinib; Temozolomide
Study Status:Terminated
Study Description:The goal of this clinical research study is to find the highest tolerable dose
of dasatinib that can be given in combination with temozolomide. The safety of
this combination will also be studied.

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Disease Group:Brain; CNS
Phase of Study:Phase I/Phase II
Treatment Agents:Dasatinib
Temozolomide
Treatment Location:Only at MDACC
Estimated Length of Stay in Houston:N/A
Supported By:Bristol-Myers Squibb Company
Return Visit:Every 4 weeks
Home Care:Patients will take dasatinib and temozolomide at home


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Physician Name:John DeGroot
Dept:Neuro Oncology
For Clinical Trial Enrollment:713-792-2883
For General Questions about Clinical Trials:800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)


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