| Exclusion Criteria: | 1) Subjects who meet any of the following criteria will be excluded from participating in the study
2) are scheduled for a partial cystectomy
3) have had a total colectomy, gastrectomy, gastric bypass, or have a functional colostomy or ileostomy
4) have an ongoing history of short bowel syndrome, chronic constipation (</=3 spontaneous BMs per week) or chronic diarrhea
5) have taken more than 3 doses of opioids (oral or parenteral) within 7 days before the day of surgery
6) have received radiation therapy to the abdomen or pelvis within 3 months of scheduled surgery
7) have received chemotherapy for bladder cancer within 1 month of scheduled surgery
8) have chemotherapy or radiation induced bowel dysfunction (eg, radiation induced colitis)
9) are pregnant (identified by a positive serum pregnancy test) or lactating, or are not postmenopausal (no menses for at least 1 year) and are of childbearing potential and not using an accepted method of birth control (ie, surgical sterilization, intrauterine contraceptive device, oral contraceptive, diaphragm, or condom in combination with contraceptive cream, jelly, or foam, or abstinence)
10) have participated in another investigational drug or medical device study within 30 days of surgery or will be enrolled in another investigational drug or medical device study or any study in which active patient participation is required outside normal hospital data collection during the course of this study
11) have clinically significant laboratory abnormalities at screening that would result in the cancellation of surgery
12) use illicit drugs or abuse alcohol
13) have a history of previous surgeries, illness, or behavior (eg, depression, psychosis) that in the opinion of the investigator might confound the study results or pose additional risk in administering the study procedures |