|Patients with leukemia often have low white blood cell counts after |
chemotherapy, which puts them at greater risk for infection. The standard of
care for preventing infections is to give these patients antibiotic,
antifungal, and antiviral drugs during the time that white blood cell counts
are low. However, many patients still develop infections during chemotherapy.
Radiated white blood cell transfusions are a standard treatment once a patient
develops a severe infection.
The goal of this clinical research study is to learn if giving unirradiated
white blood cell transfusions early in chemotherapy might delay or prevent
infections in patients with leukemia. Researchers also want to learn more
about the type and severity of any infections that do occur.