|The proposed trial will examine the effectiveness of a personalized treatment approach to managing chemotherapy-induced neuropathic cancer pain via electroencephalogram (EEG) biofeedback. |
1. Test the effects of an individualized electroencephalogram (EEG) biofeedback treatment regimen on perceptions of chemotherapy-induced neuropathic pain.
2. Examine the effects of a neurofeedback training program on other aspects of quality of life (QOL) including cancer-related symptoms, general quality of life, sleep disturbances, and fatigue.
3. Identify cortical and subcortical brain regions from the quantitative EEG that could be associated with chronic chemotherapy-induced peripheral neuropathy and examine the association between changes in EEG patterns and changes in neuropathic pain perception and the extent to which these changes mediate the effects of the intervention.
4. Examine the processes underlying the efficacy of the intervention. A biopsychosocial model drawn from existing research on pain will be evaluated to identify factors that may mediate/moderate the effects of the intervention and predict adjustment. We will evaluate coping strategies, attachment, cognitive/emotional processing, and mood.