|Study Description:||The goal of this clinical research study is to test the safety of PVX-410. |
This includes trying to find out the side effects of PVX-410 as well as trying
to find out how much of the vaccine can be given safely to patients. In
addition, the study will test your body’s immune response to the study vaccine
and whether PVX-410 works against SMM.
PVX-410 contains proteins that are usually found in myeloma cells. These
proteins may trigger a response from the immune system.
Montanide is an additive. When it is mixed with a vaccine like PVX-410, it may
help it to work better.
Hiltonol (also called Poly-ICLC) works by stimulating the immune system.
Because hiltonol stimulates the immune system, it may make PVX-410 work better.