|MDACC Study No:||2013-0097 (clinicaltrials.gov NCT No: NCT01854554)|
|Title:||A prospective Phase II randomized trial to compare intensity modulated proton radiotherapy (IMPT) vs. intensity modulated radiotherapy (IMRT) for newly diagnosed Glioblastoma (WHO Grade IV)|
|Principal Investigator:||Paul Brown|
|Treatment Agent:||Intensity Modulated Radiotherapy; Proton Therapy|
|Study Description:||The goal of this clinical research study is to compare IMRT with IMPT in |
patients with glioblastoma. Researchers want to learn about cognitive side
effects (mental status changes) that may occur, such as memory loss and
IMRT is the delivery of focused radiation therapy using photon beams and
advanced computer planning to help shape the dose in order to give the highest
possible dose to the tumor with the least dose to surrounding normal tissues.
IMPT is also focused radiation therapy similar to IMRT, but it uses proton
particles to deliver the radiation instead of photon beams. IMPT also uses
advanced computer planning in order to shape the dose to the target with the
least dose to surrounding normal tissues.