| Inclusion Criteria: | 1) Patients who have recurrent or persistent cervical cancer (any histology), with suspected or ducumented central pelvic disease, with or without sidewall disease, for which exenterative surgery is offered to remove the pelvic disease. (1) Recurrence will be defined as the reappearance of disease following a complete clinical response of >/= 1 month duration. (2) Persistence will be defined as presence of disease verified pathologically from a biopsy taken >/= 3 months from completion of primary therapy.
2) All patients must have been previously treated for the primary management of cervical cancer or its recurrence (prior therapy includes: surgery with or without postoperative radiation with/without chemotherapy, primary radiation with/without chemotherapy, neoadjuvant chemotherapy followed by surgery, or neoadjuvant chemotherapy followed by surgery +/- radiation or chemoradiation.
3) Patients must have undergone appropriate examination and imaging studies to evaluate for the presence of metastatic disease, and no distant site of metastases is identified. Patients with suspicious pelvic or para-aortic nodal disease as the only site(s) of extrapelvic disease will be allowed at the discretion of the surgeon.
4) Patients must be able and willing to complete pre-and post-operative quality of life assessments.
5) Patients must have met the pre-operative assessment requirements.
6) Patients who have met the pre-entry requirements as indicated in the Patient/Participant Evaluation section of this abstract.
7) Patients must be deemed a good surgical candidate (at surgeon's discretion).
8) Patients who have signed an approved informed consent and authorization permitting release of personal health information. |