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Web Page-Disease

Disease Phase Study No. Summary Status Total
Hide details for Advanced CancersAdvanced Cancers
  96
Hide details for Phase IPhase I
  57
2014-0763   Phase 1 Study of Mogamulizumab (KW-0761) in Combination with MEDI4736 and Mogamulizumab in Combination with Tremelimumab in Subjects with Advanced Solid Tumors  Open  
2014-0605   A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839 in Patients with Advanced and/or Treatment-Refractory Solid Tumors  Open  
2014-0495   A Phase 1, Open-Label Dose Escalation First-in-Human Study to Evaluate the Tolerability, Safety, Maximum Tolerated Dose, and Pharmacokinetics of AM0010 in Patients with Advanced Solid Tumors  Open  
2014-0384   A Phase 1 Dose-Escalation Study of LY2940680 in Patients with Advanced Cancer  Open  
2014-0338   A Phase 1 Study of LY3164530, a Bispecific Antibody Targeting MET and EGFR, in Patients with Advanced or Metastatic Cancer   Open  
2014-0193   A Phase 1b Trial of LY2606368 in Combination with
Cisplatin or Cetuximab in Advanced and/or Metastatic
Tumors
  Open  
2014-0137   An open-label Phase I dose-escalation study to evaluate
the safety, tolerability, maximum tolerated dose,
pharmacokinetics, and pharmacodynamics of the anti-
C4.4a antibody drug conjugate BAY 1129980 in
subjects with advanced solid tumors known to express
C4.4a
  Open  
2013-0969   A FIRST-IN-HUMAN PHASE 1, DOSE ESCALATION, SAFETY AND
PHARMACOKINETIC STUDY OF PF-06647263 IN ADULT PATIENTS WITH
ADVANCED SOLID TUMORS
  Open  
2013-0866   A Phase 1, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI0680 (AMP-514) in Subjects with Advanced Malignancies  Open  
2013-0833   A Phase I Trial of Regorafenib and Cetuximab in Patients with Advanced Malignancy  Open  
2013-0823   A Phase 1, Open-Label Clinical Trial Evaluating the Safety, Tolerability and Immunogenicity of Intradermally Administered ID-LV305 in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1  Open  
2013-0813   A Phase Ib Open-Label, Multi-Center, Dose Escalation and Expansion Study of Orally Administered MEK162 plus BYL719 in Adult Patients with Selected Advanced Solid Tumors   Open  
2013-0699   First-In-Human, Dose-Escalating Safety Study of Tissue Factor Specific Antibody Drug Conjugate (HuMax-TF-ADC) in Patients with Locally Advanced and/or Metastatic Solid Tumors Known to Express Tissue Factor  Open  
2013-0684   A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection  Open  
2013-0665   Phase I Study of MLN0128 (NSC# 768435) in Combination with Ziv-Aflibercept (NSC# 724770) in Patients with Advanced Cancers  Open  
2013-0616   A Phase 1 Study of LY3009120 in Patients with Advanced or Metastatic Cancer  Open  
2013-0574   Phase 1 Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of BVD-523 in Patients with Advanced Malignances  Open  
2013-0549   Phase I Safety Study of Intratumoral Injection of Clostridium novyi-NT Spores in Patients with Treatment-Refractory Solid Tumor Malignancies  Open  
2013-0525   A Phase I, First-in-Human, Dose Escalation Trial of MSC2363318A, a Dual p70S6K/Akt Inhibitor, in Subjects with Advanced Malignancies  Open  
2013-0511   A Phase I Study of MLN9708 and Vorinostat to Target Autophagy in Patients with Advanced p53 Mutant Malignancies   Open  
2013-0466   A Phase 1 Dose-Escalation and Pharmacokinetic Study of NC-4016 in
Patients With Advanced Solid Tumors or Lymphoma
  Open  
2013-0372   A Phase 1 Pharmacokinetic Study of Oral MLN9708 in Patients With Advanced Solid Tumors or Hematologic Malignancies With Varying Degrees of Liver Dysfunction  Open  
2013-0257   A Phase 1 Multiple Ascending Dose Study of DS-3032b, an oral MDM2 inhibitor, in subjects with advanced solid tumors or lymphomas  Open  
2013-0064   Phase I, Open-Label, Dose Escalation Study to Assess Safety and Tolerability of SOR-C13 in Subjects with Advanced Solid Tumors Commonly Known to Express the TRPV6 Ion Channel  Open  
2012-0985   A Phase I open-label dose escalation study with expansion to assess the safety and tolerability of INC280 in patients with c-MET dependent advanced solid tumors  Open  
2012-0795   A Phase I Trial of Ipilimumab (anti CTLA- 4 antibody) in Combination with Lenalidomide (IMiD) in Patients with Advanced Malignancies  Open  
2012-0784   A Phase I Trial of Ipilimumab (Immunotherapy) and Imatinib Mesylate (c-Kit Inhibitor) in Patients with Advanced Malignancies  Open  
2012-0748   A Phase I Trial of Vemurafenib in Combination with Cetuximab and Irinotecan in Patients with BRAF V600 Mutant Advanced Solid Malignancies  Open  
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