The purpose of this study is to find out whether different types of interventions improve attitudes regarding colorectal cancer and colorectal cancer screening among individuals who may be at increased risk for colorectal cancer because their sibling (brother or sister) was diagnosed with this disease. Specifically, this study will compare screening adherence of those who receive a generic print intervention, a tailored print intervention, and those who receive a tailored telephone counseling session and a tailored print intervention.
This study is an ongoing, NCI-funded, multi-site project. The lead institution is Fox Chase Cancer Center (FCCC). Siblings of colorectal cancer patients will be participants in the intervention study, and these siblings will be identified through patients seen at collaborating centers. As a collaborating site, MDACC will identify and contact colorectal cancer patients seen at our institution for subsequent identification and recruitment of their eligible siblings.
The primary aim of the study is:
1. To evaluate the impact of three interventions on colorectal cancer screening behaviors and intentions among siblings at increased familial risk for colorectal cancer: generic print intervention, a tailored print intervention, and a combined tailored print plus tailored telephone counseling intervention.
The secondary aims of the study are:
2. To determine whether demographic factors, medical access, physician recommendation at baseline, and colorectal cancer patient (proband) characteristics (e.g., stage of disease) moderate the impact of the interventions on colorectal screening.
3. To evaluate whether knowledge, attitude and physician recommendation variables mediate the association between the interventions and colorectal screening, and determine whether these variables are impacted by the interventions.
4. To analyze the cost of each intervention. |