|Exclusion Criteria:||1) Nursing and pregnant females. Patients of childbearing potential should practice effective methods of contraception. Should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately.|
2) Active and uncontrolled infections.
3) Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, or psychiatric illness/social situations that would limit compliance with study requirements.
4) Known ornithine transcarbamylase disorder.
5) Patients requiring continuous valproic acid treatment for the control of seizure disorders.