MDACC Study No:2012-0588 ( NCT No: NCT01656642)
Title:A Phase Ib, Open-Label Study of the Safety and Pharmacology of MPDL3280A Administered in Combination with Vemurafenib or Vemurafenib Plus Cobimetinib in Patients with Previously Untreated BRAFV600-Mutation Positive Metastatic Melanoma
Principal Investigator:Patrick Hwu
Treatment Agent:MPDL3280A; Vemurafenib
Study Status:Open
Study Description:The goal of this pre-screening test is to learn if you may be eligible to take
part in the main study. The goal of the main clinical research study is to
find the highest tolerable dose of MPDL3280A that can be given in combination
with vemurafenib (Zelboraf®) or vemurafenib plus cobimetinib (GDC-0973) to
patients with locally advanced or metastatic BRAF mutant melanoma. The safety
of the drug combination will also be studied.
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Disease Group:Melanoma
Phase of Study:Phase I
Treatment Agents:MPDL3280A
Treatment Location:Both at MDACC & and Other Sites
Estimated Length of Stay in Houston:
Supported By:Genentech, Inc.
Return Visit:
Home Care:

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Physician Name:Patrick Hwu
Dept:Melanoma Medical Oncology
For Clinical Trial Enrollment:713-792-2921
For General Questions about Clinical Trials:800-392-1611 (in U.S.A.) 713-792-6161 (outside U.S.A.)

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