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| Carol J. Etzel, PhD
Research Interests:
Statistical genetics, meta-analysis, genetic epidemiology, risk assessment models |
The research in my laboratory is directed at understanding genetic risk of disease. A strong interest in our laboratory is in constructing risk models incorporating epidemiologic and genetic data to characterize risk of lung cancer and to identify subgroups of individuals at highest risk who can be targeted for intensive intervention programs. Another interest in our laboratory is developing meta-analytic methods to combine data across genetic linkage studies. Current studies in our laboratory focus on cancer risk model development, imputing missing genetic data to improve the risk models, as well as development and testing of meta-analytic methods.
Selected Publications
Etzel CJ, Lu M, Merriman K, Liu M, Vaporacyan A, Spitz MR. An epidemiologic study of early onset lung cancer. Lung Cancer 52:129-134, 2006
Wu X, Gu J, Wu TT, Swisher SG, Liao Z, Correa AM, Liu J, Etzel CJ, Amos CI, Huang M, Chiang SS, Milas L, Hittelman WN, Ajani JA. Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer. J Clin Oncol 24:3789-3798, 2006
El-Zein RA, Schabath MB, Etzel CJ, Lopez MS, Franklin JD, Spitz MR. Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk. Cancer Res 66:6449-6456, 2006
Minard CG, Spitz MR, Wu W, Hong WK, Etzel CJ. Evaluation of glutathione S-transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary tumors in patients previously diagnosed with early-stage head and neck cancer. Cancer 106:2636-2644, 2006
Etzel CJ, Chen WV, Shepard N, Jawaheer D, Cornelis F, Seldin MF, Gregersen PK, Amos CI; for the North American Rheumatoid Arthritis Consortium. Genome-wide meta-analysis for rheumatoid arthritis. Hum Genet 119:634-641, 2006
Additional Information:
| Department: | Epidemiology |
| Department URL: | |
| Division/Section: | Cancer Prevention and Population Sciences |
| Last Updated: | 10/02/2006 |
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