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Leukemia



Emil J Freireich, DSc (Hon), MD

Research Interests:
Biology and natural history of and therapy for human leukemia


My research focuses on studying the natural history of leukemia and evaluating therapies for the disease. I interact closely with my colleagues in the Department of Leukemia. I also collaborate with the Department of Hematopathology and faculty in the Department of Laboratory Medicine in assessing clinical pathologic findings of leukemia and studying leukocyte transfusion therapy for severe antibiotic resistant infection.

As Director of Special Medical Education Programs, I organize and supervise weekly Institutional Grand Rounds "Advances in Oncology," a weekly Core Curriculum course for all graduate medical trainees, and a Graduate Medical School curriculum for training in "Patient-Oriented Research," leading to M.S. and Ph.D. degrees.


Selected Publications
Freireich EJ, Kurzrock R, Estrov Z. Metastasis--an alternative hypothesis. Cancer 103:1537-1539, 2005


Freireich EJ. The investigational new drug application--who benefits? Nat Clin Pract Oncol 3:62-63, 2006

Freireich EJ. Should terminally ill patients have the right to take drugs that pass phase I testing? Yes. BMJ 335:478, 2007

Atallah E, Cortes J, O'Brien S, Pierce S, Rios MB, Estey E, Markman M, Keating M, Freireich EJ, Kantarjian H. Establishment of baseline toxicity expectations with standard frontline chemotherapy in acute myelogenous leukemia. Blood 110:3547-3551, 2007

Tsimberidou AM, Kantarjian HM, Wen S, O'Brien S, Cortes J, Wierda WG, Koller C, Pierce S, Brandt M, Freireich EJ, Keating MJ, Estey EH. The prognostic significance of serum beta2 microglobulin levels in acute myeloid leukemia and prognostic scores predicting survival: Analysis of 1,180 patients. Clin Cancer Res 14:721-730, 2008

Additional Information:

Department: Leukemia
Department URL:
Division/Section: Cancer Medicine
Last Updated:05/05/2008


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